Held alongside as a part of SPIE PhotonicsWest 2019 event, the SPIE BIOS 2019 is the world’s largest international biomedical optics conference, encompassing clinical, translational, and fundamental research and development in the field of biomedical optics and photonics. It provides a premier technical forum for reporting and learning about the latest research and development, as well as for launching new applications and technologies. Special events include hot topics presentations, the BiOS Expo, focus on Translational and BRAIN research, and industry-leading working groups and panels.