AMS Technologies, at the upcoming LASER World of Photonics Munich event, will be presenting a diode-pumped solid-state (DPSS) laser that emits very short laser pulses (< 5 ns) of high energy (up to 20 µJ) with four wavelengths in the visible range-suitable for multispectral photoacoustic imaging. Using sophisticated technology, the new TETRA DPSS-laser can switch from pulse to pulse between these four wavelengths with a very high pulse repetition frequency of 2 kHz. The laser is based on a technical concept presented earlier this year at Photonics West by AMS Technologies. The laser specialists at AMS’ subsidiary Elforlight succeeded in doubling the maximum switching frequency from wavelength to wavelength compared to the early concept to 2 kHz.
Utilizing the Raman effect and the light of a 532 nm pump laser, the TETRA laser additionally generates the wavelengths 555 nm, 579 nm and 606 nm. A tunable optical filter separates the four wavelengths and routes one wavelength at a time to the optical output of the unit at a switching frequency of up to 2 kHz. This makes TETRA about ten times faster than tunable lasers based on OPOs (Optical Parametric Oscillators) – typical frequencies of such OPO systems range from 100 Hz to 200 Hz – while also being considerably more cost-effective.
The TETRA laser consists of two separate units: one box contains the electronics for the entire power supply and incorporates the pump laser diode. The output of this laser diode is coupled via an optical fiber to the second case, which contains the actual laser head. Due to this design, the thermal loss of the electronics and the pump diode is dissipated only in the power supply unit, and the laser head benefits from reduced thermal loading. In addition, the pump laser diode can be easily replaced at end of life without affecting the alignment of the geometry in the laser head.
Ideal for Photoacoustic Tomography in Biomedicine
The wavelengths emitted by TETRA are well matched to the absorption curves of many blood components, making the laser particularly suitable for photoacoustic tomography in biomedicine. In this technology, laser pulses stimulate organic structures to emit ultrasound waves, which are captured by suitable sensors and converted into image information. Particularly short laser pulses, such as those emitted by TETRA, generate ultrasound signals of higher frequency, which in turn lead to a better spatial resolution of the resulting images. As a further development of this method, multispectral photo-acoustic tomography uses different laser wavelengths to detect and distinguish different biomaterials.
Here the ability to switch quickly between different wavelengths offers clear advantages: during a scan of biological tissue, the absorption of four different wavelengths instead of one single wavelength can now be measured quasi-simultaneously at each individual pixel at a comparable frame rate. This avoids artifacts that can occur with multiple sequential complete scans with one wavelength each.
AMS Technologies has equipped the laser with a number of features to meet the requirements of medical safety standards for use in clinical environments. For instance a fast, fault-tolerant shutter at the laser output interrupts the beam in the event of a fault in the shortest possible time in order to avoid any hazards to a patient. With this and other features aimed at medical applications, TETRA is now ready for making its way to medical approval.
Customer-specific Variants for Many Other Applications
Although TETRA has been developed specifically to meet the requirements of multispectral photoacoustic imaging, the technology can certainly be used for many other applications as well. Based on it, AMS Technologies is ready to develop customer-specific versions that offer different wavelengths or significantly higher repetition frequencies at significantly lower pulse energy – and thus cover an even broader spectrum of requirements.
AMS will present the TETRA laser system at the LASER World of Photonics Munich trade fair from 24 to 27 June 2019 at the Munich Exhibition Centre in Hall B2, Stand B2/203, where laser experts from Elforlight (an AMS Technologies company) will be on hand to discuss the many potential applications for the laser with interested parties.
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