New Imaging Tools for Cryo-Light Microscopy

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LIGHTNING and TauSense are tools which help users increase image quality and improve the information content of the image data. LIGHTNING enhances the resolution attained under cryo conditions and TauSense helps users separate the target fluorescence signals from those of other fluorophores or even unwanted ones, such as autofluorescence and/or reflections. Both tools enable users performing cryo workflows to identify target structures within vitrified samples more reliably and accurately, particularly for cryo electron tomography.