Papers are encouraged for Frontiers in Optics (FiO) 2015, the 99th annual meeting of The Optical Society, which is being held in conjunction with Laser Science, the 31st annual meeting of the American Physical Society Division of Laser Science. The submission category Optics in Biology and Medicine includes topics such as fibers and endoscopes for biomedical applications; microscopy and OCT; optical trapping and manipulation; biophotonics for point-of-care and global health applications; general optics in biology and medicine; and novel methods for tissue imaging and therapy.