The FiO LS Frontiers in Optics + Laser Science 2022 will take place in Joseph A. Floreano Rochester Riverside Convention Center, Rochester, New York, the USA from 17th October to 20th October 2022. The conference will present more than 50 technical sessions featuring contributed oral talks and 70 invited speakers; poster sessions and a postdeadline paper session. In addition, the technical program is supplemented by three themes that represent leading-edge applications in optics and photonics. Each theme operates as a unique "workshop" within the conference.