Excelitas Releases New Light Source for Fluorescence Microscopy

Posted  by GoPhotonics

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Excelitas Technologies has introduced the new X-Cite XYLIS light source for fluorescence microscopy. It includes Excelitas’ patented LaserLED Hybrid Drive and offers a rich, broad spectrum output from 360-750 nm for exciting an extended range of fluorophores, with the advantages and simplicity of using LEDs.

The X-Cite XYLIS provides enhanced LED coverage from one end of the light spectrum to the other, closely matching the output of a mercury arc lamp while eliminating any need for bulb replacement. With a 365 nm spectral peak, it fits perfectly with the narrow DAPI filter sets that are standard in research microscopes. At the opposite end of the spectrum, it provides 735 nm excitation for Cy7, a wavelength that is not available in any other broadband LED light source at comparable prices.

The X-Cite XYLIS is the latest addition to Excelitas’ popular X-Cite product line. Incorporating the company’s’ patented LaserLED Hybrid Drive technology, the X-Cite XYLIS enables researchers to overcome the LED green gap – the 540 nm to 590 nm region of the spectrum where LED-only systems are significantly challenged. This novel technology utilizes high-efficiency lasers to excite a phosphor layer, generating a broad peak from 500 nm to 600 nm which can then be filtered to a more specific excitation band depending on the fluorophore of interest. The award-winning LaserLED Hybrid Drive is also more efficient and provides higher output than other technologies, such as luminescent rod technology, and allows the X-Cite XYLIS to be a quieter system than its predecessor, X-Cite Fire.

X-Cite XYLIS power levels for TRITC, Cy5 and Cy7 excitation are equivalent to the power of arc lamps. It is suitable for a wide range of uses from routine imaging to demanding high-speed applications. Designed for use with liquid light guides, it is compatible with modern light-guide-only microscope designs and can also be combined with X-Cite microscope adaptors to replace traditional lamp houses. It makes it possible to switch from mercury lamps to environmentally-friendly LEDs without compromising on price or performance.

The X-Cite XYLIS offers the same intuitive, easy manual operation as other X-Cite products, with speedDIAL or foot pedal, USB and TTL control options. It is compatible with the standard X-Cite command set for seamless integration with existing X-Cite 120LED software drivers.


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