Multiphoton Imaging with Gradient Index (GRIN) Lenses

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Multiphoton Imaging with Gradient Index (GRIN) Lenses

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Gradient index (GRIN) lenses solve this problem nicely. GRIN lenses are so named because of the index of refraction gradient orthogonal to the optical axis (see Figure 1). This index gradient mimics the light shaping properties of a traditional singlet lens: light may be relayed from one focal point to another. GRIN lenses designed to relay light from one end to the other may be used to bypass scattering tissue and acquire images at great depth, without removing as much overlying tissue.

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