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The Study of Circadian Rhythms and Suprachiasmatic Nucleus (SCN) Neurons

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The Study of Circadian Rhythms and Suprachiasmatic Nucleus (SCN) Neurons

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. This rhythm is governed by the master circadian pacemaker, suprachiasmatic nucleus (SCN) which can orchestrate the peripheral clocks in multiple tissues throughout the body. They have established primary cilia–mediated Sonic Hedgehog (SHH) signaling in the SCN as a novel interneuronal coupling mechanism and may lead to novel therapy of circadian disruption-linked diseases like high blood pressure, obesity and other metabolic disorders.

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