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Micronucleus Test

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Micronucleus Test

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Micronucleus test is carried out to evaluate the genotoxicity of chemical substances. Micronucleus is a smaller nucleus which are left in the cytoplasm without being taken into the main nucleus when cell division occurs due to abnormality in the chromosomes. In this test, micronucleus is counted after cells are exposed to the chemicals examined. CQ1 users can take high quality confocal images and set analysis protocols to automate the detection and counting of the micronucleus and main nucleus. In this application note, we examined the genotoxic effects of mitomycin C (MMC), which is commonly used as a positive control in micronucleus test.

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