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NFkB Translocation Analysis

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NFkB Translocation Analysis

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The CV8000 nuclear translocation analysis software enables the analysis of changes in the localization of signal molecules that transfer between cytoplasm and nuclei, such as proteins. The following is an example of the translocation analysis of NFκB, a transcription factor. NFκB plays a key role in immune reactions and is attracting attention as a target of anticancer drugs and anti-inflammatory drugs. Under normal conditions, NFκB is coupled with the inhibitor IκB and localized in the cytoplasm.

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