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Cell-by-cell Analysis of Ultra High-density HepG2 Culture

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Cell-by-cell Analysis of Ultra High-density HepG2 Culture

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For years, many types of high-density culture methods, such as spheroids, fiber scaffolds, and extracellular matrixes, have been proposed for in vitro cell-based assays. These culture systems have been recognized to more accurately simulate a cells natural environment than standard monolayer cultures on a flat substrate. Therefore, cells in high-density culture conditions are expected to exhibit responses against chemical treatments that closely resemble responses of tissues in vivo.

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