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Fluorescence Imaging & Endoscopy for Tumor Visualization and Diagnostics

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Fluorescence Imaging & Endoscopy for Tumor Visualization and Diagnostics

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Fluorescence is a phenomenon where substance that has absorbed certain wavelength of light emits it back at another wavelength. These substances are called fluorophores or fluorescent dyes. The emitted light has a longer wavelength than the absorbed one since some energy of the photon is lost in the process. The difference in wavelengths between absorbed and emitted light, called Stokes shift, allows very low background for fluorescence detection by separating it from the excitation light. The process of fluorescence generation is illustrated by the Jablonski diagram on the right.

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