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Photothermal Therapy with Platinum Nanoparticles

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Photothermal Therapy with Platinum Nanoparticles

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Photothermal therapy is a promising cancer therapy and is especially studied for brain tumors. It is based on near-infrared laser irradiation of metallic nanoparticles, which absorb the light and dissipate it as heat. The extreme heating of nanoparticles causes hyperthermia (+41-44 ⁰C) in tumors and leads to localized irreversible damage of the cancerous tissue. Cancer cells are by nature more susceptible to thermal effects than healthy cells, which further enhances the effect. Gold nanoshells are currently the only metallic nanoparticles approved by the FDA for clinical use.

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