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In Vitro Illumination using ML8500: Osmium-Based Anticancer Photosensitizer with Highest Hypoxic Activity Reported to Date

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In Vitro Illumination using ML8500: Osmium-Based Anticancer Photosensitizer with Highest Hypoxic Activity Reported to Date

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Light dosimetry experiments showed that the phototoxicity of Os-4T can be improved either by increasing the fluence or lowering the irradiance. Os-4T could be activated with both the green and the red light, but the green light was more effective. This flexibility with light parameters is beneficial when progressing to in vivo models.

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