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Corning® KBM581: Nutritious, Serum-free Media for CAR-T Cell Expansion

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Corning® KBM581: Nutritious, Serum-free Media for CAR-T Cell Expansion

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T cells that express a tumor-associated chimeric antigen receptor (CAR) show potential as an alternative adoptive cell therapy treatment for tumor patients and patients with blood cancers1 . When considering an adoptive cell therapy approach, the transfusion of a sufficient number of CAR-T cells with an appropriate phenotype is critical2 . CAR-T cell expansion requires anti-CD3/CD28 microbeads combined with IL-2, as well as the use of a nutritious, serum-free medium to ensure the safety and efficacy of CAR-T cell therapy. Corning KBM581 has been shown to be a nutritious, safe, and serum-free medium for other immune cell therapies, such as CIK and NK cells.

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