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Monitoring the Output of Pharmaceutical Hot Melt Extruders with Near-infrared Spectroscopy

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Monitoring the Output of Pharmaceutical Hot Melt Extruders with Near-infrared Spectroscopy

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  • Author: Thomas Chirkot, Sheelagh Halsey, Alan Swanborough
Recent drug discovery has been characterized by high throughput screening technologies that make a wide variety of candidates available. Although the number of new drugs available is great news in a therapeutic sense, it has drawbacks in that many of the new chemical entities have solubility issues. This can lead to problems with formulation with regard to the bioavailability of the active pharmaceutical ingredient (API).

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